Titanfall 2 is a first-person shooter in which players can control both a pilot and their Titans – mecha-style exoskeletons. The pilot has an arsenal of abilities which enhance their efficiency during combat. These abilities include invisibility cloaking and parkouring, such as double-jumping, zip-lining and wall-running with the use of a jump kit. These movements can be chained together in order to travel between locations quickly. The conflict of the game takes in "The Frontier", a region of star systems far removed from the "Core Systems" where Earth is located. The Interstellar Manufacturing Corporation (IMC) and the Frontier Militia battle for control of the Frontier; the IMC seeks to exploit the Frontier's rich resources regardless of the consequences for planetary environments and civilian populations, while the Militia fight to expel the IMC and gain independence for the Frontier.
The player assumes control of Jack Cooper, a class three rifleman from the Frontier Militia, who is sent to the alien planet of Typhon and must ally with his former squadmate's Titan named BT-7274 to fight against both local alien creatures and human enemies from the IMC.